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Name:
Areas of Specialization:
E-mail: |
Subeer S. Majumdar
Gene and protein Engineering, Genomics, Functional Genomics, Transgenic animals
subeer[at]niab[dot]org[dot]in |
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Education and training:
Dr. Subeer S. Majumdar has done his M.Sc. from Nagpur University and did his Ph.D. work at National Institute of Health & Family Welfare, New Delhi, India. He did his Postdoctoral Research at School of Medicine, Southern Illinois University, Carbondale, USA and at Department of Cell Biology and Physiology, University of Pittsburgh, USA. He was working at National Institute of Immunology, New Delhi prior to assuming this responsibility.
Research experience and contributions:
Dr. Majumdar’s lab works in the field of animal biotechnology, genomics and animal reproduction. His present research focus lies in the field of...
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Production of therapeutic proteins for animal and human in milk of farmed animals.
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Attempts to generate bulls with X chromosome bearing sperm only to increase production of female offspring (cow).
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New Methods of transgenesis for biomedical research and to facilitate production of transgenic cattle, goat and buffalo. To increase quality of herd: disease resistant and more milk yielding animals.
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Livestock genomics.
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Alternative to knock out technology, utilizing shRNA to generate transgenic animals.
Selected awards, honours and fellowships:
Fellowships of Science Academics:
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Fellow: The National Academy of Sciences, 2009
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Fellow: Indian National Science Academy, 2009
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Fellow: Indian Academy of Sciences, 2014
Membership of Professional Societies:
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Member, the Endocrine Society, USA
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Member, Society for the Study of Reproduction, USA
Selected publications:
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Souvik Sen Sharma, Subeer S. Majumdar. Transcriptional co-activator YAP regulates cAMP signaling in Sertoli cells. Molecular and Cellular Endicrinology, 2017. Volume 450, 15 July 2017, Pages 64–73, https://doi.org/10.1016/j.mce.2017.04.017.
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Kamal Mandal, Samue L. Bader, Pankaj Kumar, Dipankar Malakar, David S. Campbel, Bhola Shankar Pradhan, Rajesh K. Sarkar, Neerja Wadhwa, Souvik Sensharma, Vaibhav Jain, Robert L. Moritz, and Subeer S. Majumdar. An integrated transcriptomics-guided genomewide promoter analysis and next-generation proteomics approach to mine factor(s) regulating cellular differentiation. DNA Research, 2017, 0(0), 1–15 doi: 10.1093/dnares/dsw057.
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Suveera Dhup and Subeer S. Majumdar. Transgenesis via permanent integration of genes in repopulating spermatogonial cells in vivo. Nature Methods, 2008 5(7):601-603.
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Abul Usmani*, Nirmalya Ganguli*, Subodh K Jain, Nilanjana Ganguli, Rajesh Kumar Sarkar, Mayank Choubey, Mansi Shukla, Hironmoy Sarkar and Subeer S
Majumdar. Robust generation of transgenic mice by simple hypotonic solution mediated delivery of transgene in testicular germ cells. Molecular Therapy- Methods & Clinical Development, 2016, 3, 16076; doi:10.1038/mtm. 2016.76
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Abul Usmani, Nirmalya Ganguli, Hironmoy Sarkar, Suveera Dhup, Suryaprakash R. Batta, Manoj Vimal, Nilanjana Ganguli, Sayon Basu, P. Nagarajan and Subeer S. Majumdar. A non-surgical approach for male germ cell mediated gene transmission through transgenesis. Scientific Reports, 2013, 3, Article number: 3430 doi: 10.1038/srep03430.
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Subeer S. Majumdar, Suveera Dhup and Abu-ul Usmani. Deathless transgenesis: A new spermatogonia mediated in vivo approach for generation of transgenic mice. Nature Protocols, 2008, DOI: 10.1038/nprot.2008.124.
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Nirmalya Ganguli, Neerja Wadhwa, Abul Usmani, Neetu Kunj, Nilanjana Ganguli, Rajesh Kumar Sarkar, Soma M Ghorai, Subeer S Majumdar. An efficient method for generating a germ cell depleted animal model for studies related to
spermatogonial stem cell transplantation. Stem Cell Research and Therapy, 2016, 7: 142. doi:10.1186/s13287-016-0405-1.
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Neerja Wadhwa, Neetu Kunj, Shuchita Tiwari, Megha Saraiya, and Subeer S. Majumdar. Optimization of Embryo Culture Conditions for Increasing Efficiency of Cloning in Buffalo (Bubalus bubalis) and Generation of Transgenic Embryos via Cloning. Cloning and Stem cells. September 2009, 11(3): 387-395.
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Nirmalya Ganguli, Nilanjana Ganguli, Abul Usmani and Subeer S. Majumdar. Isolation and functional characterization of buffalo (Bubalus bubalis) β-casein promoter for driving mammary epithelial cell-specific gene expression. Journal of Biotechnology, 2015, 198, 53-59.
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Durba Pal, Suman Dasgupta, Rakesh Kundu, Sudipta Maitra, Gobardhan Das, Satinath Mukhopadhyay, Sukanta Ray, Subeer S Majumdar & Samir Bhattacharya. Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance. Nature Medicine, 2012 18(8):1279-1285.
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