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Shailesh Name:

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Dr Shailesh Sharma

Scientist D

Bioinformatics

shailesh.sharma[at]niab[dot]org[dot]in, haitoshailesh[at]gmail[dot]com
     
Education and training:

Dr Shailesh Sharma completed B.Sc. (Biology) in 2002 from Maharshi Dayanand Saraswati University, Ajmer in Rajasthan, India and M.Sc. (Bioinformatics) in 2004 from the University of Allahabad, India. He then completed the First Level Masters Program in Bioinformatics in 2006 from University of Torino, Italy through an India-Italy joint education programme, followed by Ph.D. in Structural Biology in 2010 at the Magnetic Resonance Centre, CERM, University of Florence, Italy. He obtained further training as a Post-doctoral Fellow at the Seattle Biomedical Research Institute, University of Washington, USA and the International Centre for Genetic Engineering and Biotechnology, New Delhi, India through a US-India joint research programme funded by the National Institute of Health (NIH), USA. He was working as a Project Scientist from January 2012 to December 2016 at the National Agri-Food Biotechnology Institute, Mohali, Punjab, India before joining NIAB.

Research experience and interests:

Dr. Sharma’s research experience span bioinformatics and structural biology, including application of data mining, application of bioinformatics tools, computational biology, and structure-activity relationships. His earlier work has included investigations into structural, functional and dynamic properties of metalloproteins. His research at NIAB will involve genome annotation, protein structure, target identification, and molecular dynamics simulations.

Selected awards, honours and fellowships:
  1. Session Chairman and Invited Speaker, Seminar and Training Workshop on ‘Molecular modelling, protein-protein interactions and computer-aided drug design’, University of Allahabad, India, 2010.

  2. Italian Government Scholarship in Biotechnology (processed by the Ministry Human Recourse and Development, Government of India), University of Turin, Italy, 2005-2006.

  3. Training, National High Field NMR facility, Department of Chemical Sciences, Tata Institute of Fundamental Research, Mumbai, India, 2004.

  4. Post-doctoral Fellow, US-India Joint Research Training Program, funded by Fogarty International Centre of the National Institute of Health, USA, 2010-11.

Selected publications:
  1. Shumalya, S Sharma, M Taneja, S Tyagi, K Singh, SK Upadhyay. 2017. Survey of high throughput RNA-seq data reveals potential roles for lncRNAs during development and stress response in bread wheat. Frontiers in Plant Science 8:1019

  2. S Angmo, N Tripathi, S Abbat, S Sharma, SS Singh, A Halder, K Yadav, G Shukla, R Sandhir, V Rishi, PV Bharatam, H Yadav, NK Singhal. 2017. Identification of Guanosine 5′-diphosphate as potential iron mobilizer: preventing the hepcidin-ferroportin interaction and modulating the interleukin-6/Stat-3 pathway. Scientific Reports 7:40097

  3. Shumayla, S Sharma, AK Pandey, K Singh, SK Upadhyay. 2016. Molecular characterization and global expression analysis of lectin receptor kinases in bread wheat (Triticum aestivum). PLoS ONE 11(4):e0153925

  4. M Taneja, S Tyagi, S Sharma, SK Upadhyay. 2016. Ca2+ / cation antiporters (CaCA): identification, characterization and expression profiling in bread wheat (Triticum aestivum L.). Frontiers in Plant Science 7:1775

  5. Shumayla, S Sharma, R Kumar, V Mendu, K Singh, SK Upadhyay. 2016 Genomic dissection and expression profiling revealed functional divergence in Triticum aestivum Leucine Rich Repeat Receptor Like Kinases (TaLRRKs). Frontiers in Plant Science 7:1374

  6. SK Upadhyay, S Sharma, H Singh, S Dixit, J Kumar, PC Verma, K Chandrashekar. Whitefly genome expression reveals host symbiont interaction in amino acid biosynthesis. PLoS ONE 10(5):e0153925

  7. SK Upadhyay, S Sharma. 2014. SSFinder: High-throughput CRISPR-Cas target sites prediction tool. BioMed Research International 2014:742482

  8. SK Upadhyay, S Dixit, S Sharma, H Singh, J Kumar, PC Verma, K Chandrashekar. 2013. siRNA machinery in whitefly (Bemisia tabaci). PLoS ONE 8(12:e83692

  9. S Sharma, G Cavallaro, A Rosato. 2010. A systematic investigation of multiheme c-type cytochromes in prokaryotes. Journal of Biological Inorganic Chemistry 15:559-71

  10. S Sharma, A Rosato A. 2009. Role of the N-terminal tail of metal-transporting P(1B)-type ATPases from genome-wide analysis and molecular dynamics simulations. Journal of Chemical Information and Modeling 49:76-83


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Mission: Development of sustainable and  globally competitive livestock industry through innovative technology.

Vision: To demonstrate excellence in promoting and commercializing leads in biotechnology and to produce globally competitive livestock products, pharmaceuticals and biologicals for animal health care.

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