Prof. Satya Parida
Professor Satya Parida is leading Vaccine Differentiation group
in the livestock viral disease programme, world reference laboratory, the
Pirbright Institute, UK, which carries out applied research that will help to
control foot-and-mouth disease (FMD) and Peste des Petits ruminants (PPR). He is
an adjunct professor to Murdoch University Australia and an investigator at the
Jenner Institute, Oxford University. Recently he has joined at NIAB, Hyderabad
as a visiting faculty in the infectious disease programme.
Principal Area of Research:
FMD and PPR Vaccines and diagnostics, Viral vectored based vaccine development
using reverse genetics techniques, Immunological evaluations of conventional and
new generation FMD and PPR vaccines.
The focus within the group is the development and validation of marker vaccines
and associated diagnostics for FMD and PPR. We have three lines of
investigation: (1) improving our understanding of what aspects of the immune
response are important in protection of vaccinated animals against acute and
persistent infection; (2) developing alternative means of detecting infection in
vaccinated animals; and (3) developing and evaluating improved marker vaccines
(DIVA vaccines) for FMD and PPR.
Last updated date: April 29, 2014
Pope RA, Parida S, Bailey D, Brownlie J, Barrett T, Ashley C.
Banyard. (2013) Early Events following Experimental Infection with
Peste-Des-Petits Ruminants Virus Suggest Immune Cell Targeting. PLoS ONE
8(2): e55830. doi:10.1371/journal.pone.0055830
Muniraju MB, El Harrak M, Bao J, Babu Aravindh,Banyard Ashley, Batten Carrie and
Satya Parida (2013). Complete genome sequence of peste des
petits ruminants virus recovered from an Alpine goat during a 2008 Moroccan
outbreak. Genome Announc. 2013;1(3):00096-13.
Oh Y, Fleming L, Statham B, Hamblin P, Barnett P, et al. (2012) Interferon-γ
Induced by In Vitro Re-Stimulation of CD4+ T-Cells Correlates with In Vivo FMD
Vaccine Induced Protection of Cattle against Disease and Persistent Infection.
PLoS ONE 7(9): e44365. doi:10.1371/journal.pone.0044365
Jingyue Bao, Qinghua Wang, Satya Parida, Chunju Liu, Ling
Zhang, Wenji Zhao and Zhiliang Wang. 2012, Complete Genome Sequence of a Peste
des Petits Ruminants Virus Recovered from Wild Bharal in Tibet, China. doi:
10.1128/JVI.01503-12 J. Virol. October 2012 vol. 86 no. 19
El Harrak Mehdi, Touil Nadia, Loutfi Chafiqua, Hammouchi Mustapha,
Parida Satya, Sebbar Gizlane, Chaffai Nadia, Harif Bachir, Messoudi
Nezha, Batten Carrie, and Oura Chris.A.L(2012) A reliable and reproducible
experimental challenge model for Peste-des-petits ruminants. J. Clin.
Buczkowski H, Parida S, Bailey D, Barrett T, Banyard ACA novel
approach to generating morbillivirus vaccines: Negatively marking the rinderpest
vaccine. Vaccine. 2012 2; 30(11):1927-35.
Madhanmohan M, Nagendrakumar SB, Manikumar K, Yuvaraj S, Parida S,
Srinivasan VA. (2012). Development and evaluation of a real-time
reverse transcription-loop-mediated isothermal amplification assay for rapid
serotyping of foot-and-mouth disease virus. J Virol Methods.
2012 Aug 30. [Epub ahead of print
Ko YJ, Lee HS, Park JH, Lee KN, Kim SM, Cho IS, Joo HD, Paik SG, Paton DJ,
Parida S. Field application of a recombinant protein-based
ELISA during the 2010 outbreak of foot-and-mouth disease type A in South Korea.
J Virol Methods. 2012 Jan;179(1):265-8. Epub 2011 Oct 5
Fowler V, Robinson L, Bankowski B, Cox S, Parida S, Lawlor C,
Gibson D, O'Brien F, Ellefsen B, Hannaman D, Takamatsu HH, Barnett PV.A DNA
vaccination regime including protein boost and electroporation protects cattle
against foot-and-mouth disease. Antiviral Research 94 (2012),
pp. 25-34 DOI information: 10.1016/j.antiviral.2012.02.002
Baron MD, Parida S, Oura CA.Paste des petits ruminants: a
suitable candidate for eradication? Vet Rec. 2011 Jul
Nagendrakumar SB, Srinivasan VA, Madhanmohan M, Yuvaraj S, Parida S,
Di Nardo A, Horsington J, Paton DJ. Evaluation of cross-protection
between O(1) Manisa and O(1) Campos in cattle vaccinated with foot-and-mouth
disease virus vaccine incorporating different payloads of inactivated O(1)
Manisa antigen. Vaccine. 2011 Feb 24;29(10):1906-12.
Usman Waheed, Satya Parida, Qaiser M. Khan, Manzoor Hussain,
Katja Ebert, Jemma Wadsworth, Scott M. Reid, Geoffrey H. Hutchings, Mana
Mahapatra, Donald P. King, David J. Paton and Nick J. Knowles. (2011). Molecular
Characterisation of Foot-and-Mouth Disease Viruses from Pakistan, 2005-2008.
Trans and Emerg Dis, 58:166-172.
Banyard AC, Parida S, Batten C, Oura C, Kwiatek O, Libeau
G.Global distribution of peste des petits ruminants virus and prospects for
improved diagnosis and control. J Gen Virol. 2010 Dec; 91(Pt
12):2885-2897. Epub 2010 Sep 15
Sen A, Saravanan P, Balamurugan V, Rajak KK, Sudhakar SB, Bhanuprakash V,
Parida S, Singh RK. Vaccines against peste-des-petits-ruminants
virus. Expert Rev Vaccines. 2010 Jul;9(7):785-96. Review.
Uttenthal A, Parida S, Rasmussen TB, Paton DJ, Haas B, Dundon
WG.(2010) Strategies for differentiating infection in vaccinated animals (DIVA)
for foot-and-mouth disease, classical swine fever and avian influenza.
Expert Rev Vaccines. 2010 Jan;9(1):73-87.
Sarah J. Coxa,B. Veronica Carrb, Satya Parida, Pip A. Hamblina,
Helen Prenticeb,Bryan Charlestonb, David J. Patona, Paul V. Barnett (2010)
Longevity of protection in cattle following immunisation with emergency FMD A22
serotype vaccine from the UK strategic reserve. Vaccine,
Paton DJ, Ferris NP, Hutchings GH, Li Y, Swabey K, Keel P, Hamblin P, King DP,
Reid SM, Ebert K, Parida S, Savva S, Georgiou K, Kakoyiannis
C.(2009) Investigations into the cause of foot-and-mouth disease virus
seropositive small ruminants in Cyprus during 2007. Transbound Emerg
Dis. 2009 Oct;56(8):321-328.
Satya Parida (2009) Vaccination against foot-and-mouth disease
virus: strategies and effectiveness. “Expert Review Vaccine”, 8 (3), 347-365.
Rémond M, Bruno Da Costa, Sabine Riffault b, Satya Parida,
Emmanuel Brearda, Franc¸ oise Lebretona, Stephan Zientaraa, Bernard Delmas
(2009). Infectious bursal disease subviral particles displaying the
foot-and-mouth disease virus major antigenic site. Vaccine.
D. Schley, D.J. Paton, S.J. Cox, S. Parida & S. Gubbins. The
effect of vaccination on undetected persistence of foot-and-mouth disease virus
in cattle herds and sheep flocks. Epidemiology and Infection.
Epidemiol. Infect. (2009), 137, 1494–1504
S Parida, L Fleming, Y Oh, M Mahapatra, P Hamblin, J Gloster
and D J Paton. (2008) Emergency vaccination of sheep against foot-and-mouth
disease: significance and detection of subsequent sub-clinical infection.
Vaccine 26, 3469-3479
Bronsvoort B.M.deC., Parida S., Handel I, McFarland S., Fleming
L., Hamblin P., and Kock R.(2008) Serological survey for foot-and-mouth disease
in wildlife in East Africa and parameter estimate of the Ceditest NSP ELISA for
buffalo. Clin Vaccine Immunol. 2008 Jun;15(6):1003-11.
Vannier P., Capua I., Le Potier M.F., Mackay D., Muylkens B., Parida S.,
Paton D.J., Thiry E. (2007). Marker vaccines and impact of their use on
diagnostic and prophylactic measures (Review).
S Parida, L Fleming, Y Oh, M Mahapatra, Hamblin P, J Gloster, C
Doel, S Gubbins and D J Paton (2007). Reduction of foot-and-mouth disease (FMD)
virus load in nasal excretions, saliva and exhaled air of vaccinated pigs
following direct contact challenge. Vaccine, 25 (45),
Parida S, Mahapatra m, Saikumar, Das Subash, Baron Michael,
Anderson J and Barrett T (2007). Rescue of chimeric rinderpest virus with the
nucleocapsid protein derived from Peste des Petits Ruminants virus: Use as a
marker vaccine. Journal of General Virology, 88:7, 2019-2027.
Perkins J, Parida S, Clavijo A. (2007). Use of a standardized
bovine serum panel to evaluate a multiplexed nonstructural proteín antibody
assay for serological surveillance of Foot-and-mouth disease. Clinical
and Vaccine Immunology. Nov 07. 1472-1482.
Satya Parida, Lucy Fleming, Debi Gibson, Pip A. Hamblin,
Santina Grazioli, Emiliana Brocchi and David J. (2007). Bovine serum panel for
evaluation of FMDV non structural protein antibody tests. In press". J.
Vet. Diagn. Invest. 19(5),:539-544.
Sarah Cox, Satya Parida, Charlotte Voyce, Scott Reid, Pip
Hamblin, Geoff Hutchings, David J Paton, Paul Barnett (2007). Further evaluation
of higher potency vaccines for early protection of cattle against FMDV direct
contact challenge. Vaccine, 25 (44):7687-7695.
D.J. Sammin, D. J. Paton, S. Parida, N. P. Ferris, G. H Gibson,
M. Corteyn, N. J. Knowles, J. – F. Valarcher , P. A. Hamblin, L. Feming, G.
Gwaze, K. J. Sumption. (2007). Evaluation of laboratory tests for SAT serotypes
of foot-and-mouth disease virus withspecimens collected from convalescent cattle
in Zimbabwe. Vet Record. 160: 647-654.
Hema M, Nagendrakumar SB, Yamini R, Chandran D, Rajendra L, Thiagarajan D,
Parida S, Paton DJ, Srinivasan VA, (2007) Chimeric
tymovirus-like particles displaying foot-and-mouth disease virus non-structural
protein epitopes and its use for detection of FMDV-NSP antibodies.
Vaccine, 25(25): 4784-4794.
Parida S, Anderson J, Cox S, Barnet PV and paton DJ. (2006).
Secretory Ig A as an indicator of oropharyngeal FMDV replication.
M. Mahapatra, S. Parida, M. D. Baron and T. Barrett. (2006).
PPRV matrix (M) and glycoproteins (F/H) function better as a homologous complex:
Development of a marker vaccine for PPRV. Journal of General Virology,
Parida S, Cox S.J., Reid SM, Hamblin P, Barnet PV, Inoue T.,
Anderson J, Paton David. (2005). The application of new techniques to the
improved detection of persistently infected cattle after vaccination and contact
exposure to foot-and-mouth disease. Vaccine 23:5186-5195.
Parida S, Mahapatra M., Hawes Pippa, Baron Michael, Monaghan
Paul and Barrett Tom.(2005). Importance of the extracellular and
cytoplasmic/transmembrane domains of the haemagglutinin protein of rinderpest
virus for recovery of viable virus from cDNA copies. Virus Research
Parida S, OH Yooni, Reid Scott, Cox Sarah, Mahapatra Mana,
Statham Bob, Barnet Paul, Anderson John, Charleston Bryan and Paton David.(
2006). Interferon-γ production in vitro from whole blood of foot-and-mouth
disease virus (FMDV) vaccinated and infected cattle after incubation with
inactivated FMDV. Vaccine 24:964-969.
SJ Cox , Voyce C, Parida S, Reid S.M, Hamblin P. A, Paton D.J
and Barnett P.V. (2006). Effect of antigen payload on protection, sub-clinical
infection and persistence following direct contact challenge, Vaccine
Brocchi, E., I. E. Bergmann, A. Dekker, D. J. Paton, D. J. Sammin, M. Greiner,
S. Grazioli, F. De Simone, H. Yadin, B. Haas, N. Bulut, V. Malirat, E. Neitzert,
N. Goris, S. Parida, K. Sorensen, and K. De Clercq (2006).
Comparative performance of six ELISAs for antibodies to the non-structural
proteins of foot-and-mouth disease. Vaccine, 24:6966-6979.
Paton DJ, Clercq KD, Greiner M, Dekker A, Brocchi E, Bergmann I, Sammin DJ,
Gubbins S, Parida. (2006). Application of non-structural
protein antibody tests in substantiating freedom from foot-and-mouth disease
virus infection after emergency vaccination of cattle. Vaccine,
Toru Inoue, Satya Parida, David J Paton, Wilai
Linchongsubongkoch, David Mackay, Yooni Oh, Dilok Aunpomma, Simon Gubbins,
Takakiyo Saeki. (2006). Development and evaluation of an indirect ELISA to
detect Foot-and-Mouth disease virus non-structural protein antibody using a
chemically synthesized 2B peptide as antigen. Journal of Veterinary
Dignostics and Investigation, 18:545-552.
Kai Frolich, Chris Hamblin, Satya parida, Eeva Tuppurainen and
Elvira Schettler.(2006). Serological survey on potential diseases agents of free
ranging cervids in six selected National parks from Germany. Journal of
wildlife Diseases, 42(4):836-843.
Baron M.D., Banyard A., Parida S. and Barrett T. 2005. The
Plowright vaccine strain of rinderpest virus has attenuating mutations in most
genes. Journal of General Virology, 86:1093-1101.
S. Reid, Parida S, King D P, Hutching G, Shaw A, Feris N, Zhang
Z, Hilerton E,Paton DJ (2005). Use of automated real-time RT-PCR to detect foot
and mouth disease virus in milk. Vterinary Research, 37
Cox S.J, Voyce C, Parida S, Reid S.M, Hamblin P. A, Paton D.J
and Barnett P.V.(2005) Protection against direct contact challenge following
emergency FMD vaccination of cattle and the effect on virus excretion from the
oropharynx. Vaccine, 23: 1106-1113
Mahapatra M, Parida S, Egziabher BG, Diallo A, Barrett T.
(2003). Sequence analysis of the phosphoprotein gene of Peste des petits
ruminants (PPR) Virus: Editing of the Gene Transcript. Virus Research,
Forsyth MA, Parida S, Alexandersen S, Belsham GJ, Barrett T.
(2003). Rinderpest virus lineage differentiation using RT-PCR and SNAP-ELISA.
J Virol Methods. 107(1):29-36.