|
|
 |
Name:
Designation:
Areas of Specialization:
E-mail: |
Dr Paresh Sharma
Scientist-D
Molecular and Cellular Biology, Immunology, Genomics, Proteomics
paresh[at]niab[dot]org[dot]in |
| |
|
|
Education and Training:
Dr. Paresh Sharma received his PhD (2010) in Molecular Parasitology from BITS Pilani, Rajasthan, during which time he worked at National Institute of Pathology for his research work. He did his post-doctoral work in Malaria Biology at the National Institute of Allergy and Infectious Diseases (NIAID), the National Institute of Health (NIH), USA from 2010-2013. He joined the National Institute of Animal Biotechnology in January 2013.
Research experience and contributions:
Dr. Sharma’s research experience spans Molecular Parasitology, Microbiology and Immunology. His research interest has been focused on understanding mechanisms of pathogenesis behind major diseases using functional genomics and proteomics approaches. His current research encompasses functional genomics of disease pathogenesis and identification of disease resistance markers against intracellular pathogens in livestock. The main aims are to understand the genetic basis of variation in the host’s response to pathogens and study the host pathogen interaction. Identifying the genes involved in immune response/host parasite interaction/disease resistance could lead to development of tools/strategies to reduce and control disease in livestock.
Selected publications:
-
S Chakraborty, S Roy, H Mistry, N George, S Murthy, V Bhandari, P Sharma. Potential Sabotage of Host Cell Physiology by Apicomplexan Parasites for Survival Benefits. (2017) Frontiers of Immunology; 8:1261.
-
Mahato S, Mistry HU, Chakraborty S, Sharma P, Saravanan R, Bhandari V. Identification of Variable Traits among the Methicillin Resistant and Sensitive Coagulase Negative Staphylococci in Milk Samples from Mastitic Cows in India. Front Microbiol. 2017; 8:1446.
-
N George, V Bhandari, P Sharma. 2017. Phylogenetic relationship and genotypic variability in Anaplasma marginale strains causing anaplasmosis in India. Infection Genetics and Evolution 48:71-5.
-
V Sharma, P Sharma, A Selvapandiyan, P Salotra. 2016. Leishmania donovani- specific Ub-related modifier-1: an early endosome-associated ubiquitin-like conjugation in Leishmania donovani. Molecular Microbiology 99(3):597-610.
-
H Mistry, P Sharma, S Mahato, R Saravanan, PA Kumar, V Bhandari. 2016. Prevalence and characterization of oxacillin susceptible mecA-positive clinical isolates of Staphylococcus aureus causing bovine mastitis in India. PLoS ONE 11:e0162256.
-
N George, V Bhandari, DP Reddy, P Sharma. 2015. Emergence of new genotype and diversity of Theileria orientalis parasites from bovines in India. Infection Genetics and Evolution 36:27-34.
-
N George, V Bhandari, DP Reddy, P Sharma. 2015. Molecular and phylogenetic analysis revealed new genotypes of Theileria annulata parasites
from India. Parasite Vectors 8:468.
-
P Sharma, K Rayavara, D Ito, K Basore, SA Desai SA. 2015. A CLAG3 mutation in an amphipathic transmembrane domain alters malaria parasite nutrient channels and confers leupeptin resistance. Infection and Immunity 83(6):2566-74.
-
P Sharma, K Wollenberg, M Sellers, K Zainabadi, K Galinsky, E Moss, W Nguitragool, D Neafsey, SA Desai. 2013. An epigenetic antimalarial resistance mechanism involving parasite genes linked to nutrient uptake. Journal of Biological Chemistry 288(27):19429-40.
-
AD Pillai, R Addo, P Sharma, W Nguitragool, P Srinivasan, SA Desai SA. 2013. Malaria parasites tolerate broad range of ionic environments and do not require host cation remodeling. Molecular Microbiology 88(1):20-34.
Detailed Profile
|
|
|
|