NIAB
  Skip Navigation Links  
  Digital India
 
Dr. Paresh Sharma Name:

Designation:

Areas of Specialization:

E-mail:
Dr Paresh Sharma

Scientist-C

Molecular and Cellular Biology, Immunology, Genomics, Proteomics

paresh[at]niab[dot]org[dot]in
     
Education and Training:

Dr. Paresh Sharma received his PhD (2010) in Molecular Parasitology from BITS Pilani, Rajasthan, during which time he worked at National Institute of Pathology for his research work. He did his post-doctoral work in Malaria Biology at the National Institute of Allergy and Infectious Diseases (NIAID), the National Institute of Health (NIH), USA from 2010-2013. He joined the National Institute of Animal Biotechnology in January 2013.


Research experience and contributions:

Dr. Sharma’s research experience spans Molecular Parasitology, Microbiology and Immunology. His research interest has been focused on understanding mechanisms of pathogenesis behind major diseases using functional genomics and proteomics approaches. His current research encompasses functional genomics of disease pathogenesis and identification of disease resistance markers against intracellular pathogens in livestock. The main aims are to understand the genetic basis of variation in the host’s response to pathogens and study the host pathogen interaction. Identifying the genes involved in immune response/host parasite interaction/disease resistance could lead to development of tools/strategies to reduce and control disease in livestock.


Selected publications:
  1. N George, V Bhandari, P Sharma. 2017. Phylogenetic relationship and genotypic variability in Anaplasma marginale strains causing anaplasmosis in India. Infection Genetics and Evolution 48:71-5.

  2. V Sharma, P Sharma, A Selvapandiyan, P Salotra. 2016. Leishmania donovani- specific Ub-related modifier-1: an early endosome-associated ubiquitin-like conjugation in Leishmania donovani. Molecular Microbiology 99(3):597-610.

  3. N George, V Bhandari, DP Reddy, P Sharma. 2015. Emergence of new genotype and diversity of Theileria orientalis parasites from bovines in India. Infection Genetics and Evolution 36:27-34.

  4. H Mistry, P Sharma, S Mahato, R Saravanan, PA Kumar, V Bhandari. 2016. Prevalence and characterization of oxacillin susceptible mecA-positive clinical isolates of Staphylococcus aureus causing bovine mastitis in India. PLoS ONE 11:e0162256.

  5. N George, V Bhandari, DP Reddy, P Sharma. 2015. Molecular and phylogenetic analysis revealed new genotypes of Theileria annulata parasites from India. Parasite Vectors 8:468.

  6. P Sharma, K Rayavara, D Ito, K Basore, SA Desai SA. 2015. A CLAG3 mutation in an amphipathic transmembrane domain alters malaria parasite nutrient channels and confers leupeptin resistance. Infection and Immunity 83(6):2566-74.

  7. P Sharma, K Wollenberg, M Sellers, K Zainabadi, K Galinsky, E Moss, W Nguitragool, D Neafsey, SA Desai. 2013. An epigenetic antimalarial resistance mechanism involving parasite genes linked to nutrient uptake. Journal of Biological Chemistry 288(27):19429-40.

  8. AD Pillai, R Addo, P Sharma, W Nguitragool, P Srinivasan, SA Desai SA. 2013. Malaria parasites tolerate broad range of ionic environments and do not require host cation remodeling. Molecular Microbiology 88(1):20-34.

  9. W Nguitragool, AAB Bokhari, AD Pillai, K Rayavara, P Sharma, B Turpin, L Aravind, SA Desai. 2011. Malaria parasite clag genes determine nutrient uptake channel activity on infected red blood cells. Cell 145:665–77.

  10. G Sreenivas, P Sharma, R Duncan, P Salotra, HL Nakhasi. 2011. Mitochondrial associated Ubiquitin fold modifier-1 mediated protein conjugation in Leishmania donovani. PLoS ONE 6(1):e16156.

Detailed Profile





 
Mission & Vision

Mission: Development of sustainable and  globally competitive livestock industry through innovative technology.

Vision: To demonstrate excellence in promoting and commercializing leads in biotechnology and to produce globally competitive livestock products, pharmaceuticals and biologicals for animal health care.

Important Links


Advertisement No. 9/2017New

Advertisement No. 10/2017New

Advertisement No. 8/2017New

GST DetailsNew

TendersNew

Advertisement No. 7/2017

Forthcoming NIAB

Opportunities for Indian Scientists Working Abroad

Integrity Pledge

Digital NIAB

SPMS

Digital India Week

Annual Reports
 
  [ Log In ]  | RTI | DisclaimerContact | Copyrights © NIAB | Last updated date: 20-Aug-2017