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Nagendra Hegde Name:


Designation:


Areas of Specialization:


E-mail:
Nagendra R. Hegde


Scientist-G


Disease epidemiology, Host-pathogen interaction, Molecular pathogenesis, Virulence determinants, Vaccines, Diagnostics


hegde[at]niab[dot]org[dot]in
     
Education and training:

Dr. Nagendra R. Hegde completed B.V.Sc. (1989) and M.V.Sc. (1992; Veterinary Microbiology and Public Health – Virology) from the University of Agricultural Sciences, Bangalore, India, and Ph.D. (1998; Veterinary & Biomedical Sciences – Immunology) from the University of Nebraska, U.S.A. He then worked as a Post-doctoral Fellow (Aug 1998 to Mar 2004) and then as a Research Assistant Professor (Apr 2004 to May 2006) at the Oregon Health & Science University, U.S.A. Before joining NIAB on 30-03-2017, he was a Group Leader (Aug 2006 to Mar 2014) and then the Associate Director (Apr 2014 to Mar 2017) of Ella Foundation, Hyderabad, India.


Research experience and interests:

Dr. Hegde’s research experience spans veterinary virology, immunology and microbiology. His major contribution has been in virology, where he has worked on epidemiology, genomics, diagnosis and prevention as well as interaction with host cells of animal (as well as human) DNA and RNA viruses. In immunology, he has worked on bovine major histocompatibility complex (MHC) and cell-mediated immunity (CMI). In microbiology, he has worked on epidemiology, diagnosis and preventive measures for bovine mastitis-causing pathogens. His research interests are to understand the epidemiology, genomics, and biology of important livestock diseases, to devise protective measures for these diseases, and to elucidate fundamentals of immunological responses.


Selected awards, honours and fellowships:
  1. Academic Editor, PLoS ONE; Editorial Board, Clinical and Vaccine Immunology; Reviewer, several journals

  2. Reviewer, several journals

  3. Member, National Advisory Committee, Veterinary Virology Section, ViroCon 2016, International Conference on Global Perspectives in Virus Disease Management, Bengaluru, India, 2016

  4. Chairman, Organizing Committee (Veterinary), National Conference on Emerging and Re-emerging Viral Outbreaks in India – Clinical Challenges and Management, Hyderabad, India, 2015

  5. Contributed to the development of the World Health Organization’s draft guidelines on the quality, safety and efficacy of Ebola vaccines, 2015

Selected publications:

  1. D Hemadri, S Maan, MM Chanda, PP Rao, K Putty, Y Krishnajyothi, GH Reddy, V Kumar, K Batra, YV Reddy, NS Maan, YN Reddy, KP Singh, SB Shivachandra, NR Hegde, H Rahman, PPC Mertens. 2017. Dual infection with bluetongue virus serotypes and first time isolation of serotype 5 in India, Transboundary and Emerging Diseases, Epub ahead of print, 2016 Dec 21.

  2. J Gogoi-Tiwari, V Williams, CB Waryah, P Costantino, H Al-Salami, S Mathavan, K Wells, HK Tiwari, N Hegde, S Isloor, H Al-Sallami, T Mukkur. 2017. Mammary gland pathology subsequent to acute infection with strong versus weak biofilm forming Staphylococcus aureus bovine mastitis isolates: a pilot study using non-invasive mouse mastitis model. PLoS ONE 12(1):e0170668.

  3. YV Reddy, Y Krishnajyothi, B Susmitha, BV Devi, Y Brundavanam, SR Gollapalli, N Karunasri, B Sonali, K Kavitha, SR Patil, G Sunitha, K Putty, GH Reddy, YN Reddy, NR Hegde, PP Rao. 2016. Molecular typing of bluetongue viruses isolated over a decade in South India. Transboundary and Emerging Diseases 63(5):e412-8.

  4. Y Krishnajyothi, S Maan, K Kandimalla, NS Maan, RB Tutika, YV Reddy, A Kumar, N Mrunalini, GH Reddy, K Putty, SM Ahmed, YN Reddy, D Hemadri, KP Singh, PPC Mertens, NR Hegde, PP Rao. 2016. Isolation of bluetongue virus 24 from India – an exotic serotype to Australasia. Transboundary and Emerging Diseases 63(4):360-4.

  5. PL Preethirani, S Isloor, S Sundareshan, V Nuthanalakshmi, K Deepthikiran, AY Sinha, D Rathnamma, K Nithin Prabhu, R Sharada, TK Mukkur, NR Hegde. 2015. Isolation, biochemical and molecular identification, and in-vitro antimicrobial resistance patterns of bacteria isolated from bubaline subclinical mastitis in South India. PLoS ONE 10(11):e0142717.

  6. PP Rao, YV Reddy, NR Hegde. 2015. Isolation and complete genome sequencing of bluetongue virus serotype 12 from India. Transboundary and Emerging Diseases 62(5):e52-9.

  7. J Gogoi-Tiwari, CB Waryah, R Sunagar, HB Veeresh, V Nuthanalakshmi, PL Preethirani, R Sharada, A Bhat, S Isloor, H Al-Salami, NR Hegde, TK Mukkur*. Typing of Staphylococcus aureus isolated from bovine mastitis cases in Australia and India. Australian Veterinary Journal 3(8):278-82.

  8. S Manjunath, PG Kulkarni, K Nagavelu, RJ Samuel, S Srinivasan, N Ramasamy, NR Hegde, RS Gudde. 2015. Sero-prevalence of rodent pathogens in India. PLoS ONE 10(7):e0131706.

  9. S Maan, NS Maan, M Belaganahalli, PP Rao, KP Singh, D Hemadri, K Putty, A Kumar, K Batra, Y Krishnajyothi, BS Chandel, GH Reddy, K Nomikou, YN Reddy, H Attoui, NR Hegde, PP Mertens. 2015. Full genome sequencing as a basis for molecular epidemiology of bluetongue virus in India. PLoS ONE 10(6):e0131257.

  10. J Gogoi-Tiwari, CB Waryah, KY Eto, M Tau, K Wells, P Costantino, HK Tiwari, S Isloor, N Hegde, TK Mukkur. 2015. Relative distribution of virulence-associated factors among Australian bovine Staphylococcus aureus isolates: potential relevance to development of an effective bovine mastitis vaccine. Virulence 6(5):419-23.

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