Dr. Madhuri Subbiah
Dr. Madhuri Subbiah is a veterinarian by profession and
received her Ph.D. in Molecular Virology from University of Maryland, College
Park in Maryland, USA in 2010. During her doctoral studies in the laboratory of
Dr. Siba. K. Samal, she characterized Avian Paramyxovirus serotype 2 (APMV-2)
strains and also established reverse genetics system for APMV-2 prototype strain
Yucaipa. Dr. Madhuri had previously worked as Deputy Manager, Platform
Technologies, Anthem Biosciences Pvt. Ltd., Bangalore, where she and her team
developed novel cell based high throughput enabled assays for drug screening.
She joined the National Institute of Animal Biotechnology (NIAB) in November
2012 as Scientist C. Her research interests are to understand the molecular
mechanisms of viral pathogenesis, to comprehend host-pathogen interactions and
virus evasion of host immune response. Her major focus at NIAB will be to
apply this knowledge for developing on-farm viral diagnostics and novel
Naveen Gujjar, Shubhada K. Chothe, Shashikant Gawai, Ruth Nissly, Gitanjali Bhushan, Vijayarani Kanagaraj, Bhushan M. Jayarao, Kumanan Kathaperumal, Madhuri Subbiah and Suresh V. Kuchipudi. Co-expression of sialic acid receptors compatible with avian and human influenza virus binding in emus (Dromaius novaehollandiae). Virology 500: 14-121, 2017.
SP Vaidyanathan, S Gawai, M Subbiah. Elucidation of the role of non-structural viral protein (W) of Newcastle disease virus. International Journal of Infectious Diseases 45: 337-338, 2016.
Karnati HK, Pasupuleti SR, Kandi R, Undi RB, Sahu I, Kannaki TR, Subbiah M, Gutti RK. TLR-4 signalling pathway: MyD88 independent pathway up-regulation in chicken breeds upon LPS treatment. Vet Res Commun. Mar; 39(1):73-8, 2015.
Rajakrishna L, Krishnan Unni S, Subbiah M, Sadagopan S, Nair
AR, Chandrappa R, Sambasivam G, Sukumaran SK. Validation of a human cell based
high-throughput genotoxicity assay 'Anthem's Genotoxicity screen' using ECVAM
recommended lists of genotoxic and non-genotoxic chemicals. Toxicol In
Vitro. Feb; 28 (1): 46-53, 2014. Epub 2013 Jul 9.
Xiao S, Khattar SK, Subbiah M, Collins PL and Samal
SK. Mutation of the F protein cleavage site of avian paramyxovirus-7 results in
furin cleavage, fusion promotion and increased replication in vitro, but not
increased replication, tissue tropism, or virulence in chickens. Journal
of Virology. Jan; 86(7): 3828-3838, 2012.
Kim SH, Subbiah M, Samuel AS, Collins PL and Samal SK. Roles of
the fusion and hemagglutinin-neuraminidase proteins in replication, tropism, and
pathogenicity of avian paramyxoviruses. Journal of Virology.
Subbiah M, Khattar SK, Collins PL and Samal SK. Mutations in the fusion
protein cleavage site of avian paramyxovirus serotype 2 increase cleavability
and syncytium formation but do not increase viral virulence in chickens.
Journal of Virology. Jun;85(11):5394-5405, 2011.
Samuel AS, Subbiah M, Shive H, Collins PL and Samal SK.
Experimental infection of hamsters with avian paramyxovirus serotypes 1 to 9.
Veterinary Research. Feb;42(1):38, 2011.
Complete genome sequence of Avian Paramyxovirus serotype 1, Newcastle disease virus strain Komarov. GenBank Accession # KT445901.1
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