Dr. Girish K. Radhakrishnan
Dr. Girish K Radhakrishnan received his PhD in Biotechnology
from School of Biotechnology, Madurai Kamaraj University in 2006. He did his
postdoctoral research at the University of Wisconsin-Madison in the areas of
microbiology and immunology. He joined the National Institute of Animal
Biotechnology in December 2012 as Scientist D. His research interests include
understanding the virulence mechanisms of the infectious intracellular bacterial
pathogen, Brucella and development of novel vaccines and diagnostic tools for
animal and human brucellosis.
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Smith, J. A. Magnani. D, Kahn. M , Harms. J, Durward. M,
Radhakrishnan. G, Liu, Y-P and Splitter, G (2013). Brucella Induces an
Unfolded Protein Response via TcpB that Supports Intracellular Replication in
Macrophages. PLoS Pathogen, 9(12): e1003785.
and Splitter, G. (2012)
Modulation of host microtubule dynamics by pathogenic bacteria. Biomolecular Concepts
3 (6), 571–580.
Gupta VK, Radhakrishnan G, Harms J, Splitter
G. (2012) Invasive Escherichia coli vaccines expressing Brucella melitensis
outer membrane proteins 31 or 16 or periplasmic protein BP26 confer protection
in mice challenged with B. melitensis. Vaccine 30, 4017-4022.
Durward M, Radhakrishnan G, Harms J, Bareiss C, Magnani D and
Splitter, G. A (2012) Active Evasion of CTL Mediated Killing and Low Quality
Responding CD8+ T Cells Contribute to Persistence of Brucellosis. PLoS
ONE 7(4): e34925.
Radhakrishnan G, Harms, J and Splitter, G (2011). Modulation of
microtubule dynamics by a TIR domain containing protein from an intracellular
pathogen Brucella. Biochemical Journal 439 (1) 79-83.
Radhakrishnan G, and Splitter, G. (2010). Biochemical and
functional analysis of TIR domain-containing protein from Brucella melitensis.
Biochemical and Biophysical Research Communications 397(1)
Radhakrishnan G, K., Yu, Q., Harms, J. S., Splitter, G. A.
(2009). Brucella TIR domain-containing protein mimics properties of the
toll-like receptor adaptor protein TIRAP. Journal of Biological
Chemistry 284(15): 9892-9898.
Last updated date: February 14, 2014