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Dr. Girish K. Radhakrishnan
Scientist D
Email: girish[at]niab[dot]org[dot]in

Dr. Girish K Radhakrishnan received his PhD in Biotechnology from School of Biotechnology, Madurai Kamaraj University in 2006. He did his postdoctoral research at the University of Wisconsin-Madison in the areas of microbiology and immunology. He joined the National Institute of Animal Biotechnology in December 2012 as Scientist D. His research interests include understanding the virulence mechanisms of the infectious intracellular bacterial pathogen, Brucella and development of novel vaccines and diagnostic tools for animal and human brucellosis.
  Dr. Girish K. Radhakrishnan, Scientist D

Recent Publications:
  • Smith, J. A. Magnani. D, Kahn. M , Harms. J, Durward. M, Radhakrishnan. G, Liu, Y-P and Splitter, G (2013). Brucella Induces an Unfolded Protein Response via TcpB that Supports Intracellular Replication in Macrophages. PLoS Pathogen, 9(12): e1003785. doi:10.1371/journal.ppat.1003785).

  • Radhakrishnan G, and Splitter, G. (2012) Modulation of host microtubule dynamics by pathogenic bacteria. Biomolecular Concepts 3 (6), 571–580.

  • Gupta VK, Radhakrishnan G, Harms J, Splitter G. (2012) Invasive Escherichia coli vaccines expressing Brucella melitensis outer membrane proteins 31 or 16 or periplasmic protein BP26 confer protection in mice challenged with B. melitensis. Vaccine 30, 4017-4022.

  • Durward M, Radhakrishnan G, Harms J, Bareiss C, Magnani D and Splitter, G. A (2012) Active Evasion of CTL Mediated Killing and Low Quality Responding CD8+ T Cells Contribute to Persistence of Brucellosis. PLoS ONE 7(4): e34925.

  • Radhakrishnan G, Harms, J and Splitter, G (2011). Modulation of microtubule dynamics by a TIR domain containing protein from an intracellular pathogen Brucella. Biochemical Journal 439 (1) 79-83.

  • Radhakrishnan G, and Splitter, G. (2010). Biochemical and functional analysis of TIR domain-containing protein from Brucella melitensis. Biochemical and Biophysical Research Communications 397(1) 59-63.

  • Radhakrishnan G, K., Yu, Q., Harms, J. S., Splitter, G. A. (2009). Brucella TIR domain-containing protein mimics properties of the toll-like receptor adaptor protein TIRAP. Journal of Biological Chemistry 284(15): 9892-9898.

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Last updated date: February 14, 2014
 
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Mission: Development of sustainable and  globally competitive livestock industry through innovative technology.

Vision: To demonstrate excellence in promoting and commercializing leads in biotechnology and to produce globally competitive livestock products, pharmaceuticals and biologicals for animal health care.

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