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Dr. Syed M. Faisal
Scientist D
Email: faisal[at]niab[dot]org[dot]in

Dr. Syed Faisal received his PhD in Biotechnology from Aligarh Muslim University in 2006. He did his postdoctoral research at College of Veterinary Medicine, Cornell University, USA in the areas of Microbiology and Immunology. He worked for short period of time as Research Scientist at Carver College of Medicine, University of Iowa, USA before joining NIAB.

Dr. Faisal has several publications in International Journals and has received various awards like Maurice R Hillman early stage career investigation award 2009 from National Foundation of Infectious Diseases, USA, Ramalingaswami Re-Entry Fellowship 2012 from DBT, Govt. of India, and Edward Jenner Vaccine Award 2014 from International Society for Vaccines, USA. He is member of International Society of Vaccines and also serving in the Editorial board of various International Journals.

His research interests include understanding the host response and molecular pathogenesis of zoonotic/infectious diseases for development of novel vaccines and diagnostic tools. His research is also focused on developing novel veterinary adjuvants and drug delivery systems.

Selected Publications:
  • Ramakrishna Bulugonda, Kotha Anil Kumar, Gangappa D, Muralidhara Rao* Syed M. Faisal* Mangiferin from Pueraria tuberosa reduces inflammation via inactivation of NLRP3 inflammasome. Scientific Reports 2017 Feb 20; 7: 42683. (*corresponding author).

  • Syed M. Faisal*, Vivek Verma, Subathra M, Anil K Sunkara, Sarwar Azam, Mohd Akif, Mirza S Baig, Chang YF, (2016). Leptospira surface protein Lsa21 induce proiflammatory cytokines by Toll like receptor 2 and 4 mediated signaling pathways. Scientific Reports 2016, Dec 20; 6: 39530. (*corresponding author).

  • Syed M. Faisal*, Joy Scaria and Yung Fu Chang. Immunostimulatory Fusogenic and Conventional Liposome Adjuvants Induce Qualitatively and Quantitatively Distinct Innate and Adaptive Immune Responses. Journal of Immune Research 2015; 2(2): 1020 (*corresponding author).

  • Syed M. Faisal, Chen JW, McDonough SP and Yung-Fu Chang. Evaluation of Mycobacterium avium subsp. paratuberculosis LeuD mutant as vaccine candidate against challenge in caprine model. Clinical Vaccine Immunology 2013 Apr 20;4: 572-581.

  • Syed M. Faisal, Yan F, McDonough SP and Yung-Fu Chang. Evaluation of immune response and protective efficacy of live attenuated salmonella vaccine expressing antigens of Mycobacterium avium subsp. paratuberculosis against Johne's disease in goat model. PLOS ONE 2013, Aug 9; 8(8): e70171.

  • Syed M. Faisal, Chen JW, McDonough SP and Yung-Fu Chang. Immunostimulatory and antigen delivery properties of liposomes made up of total polar lipids from non-pathogenic bacteria leads to efficient induction of both innate and adaptive immune response. Vaccine 2011; (29): 2381-2391.

  • Syed M. Faisal, WeiWei Yan, Sean P. McDonough, and Yung-Fu Chang. Leptosome entrapped protective antigens conferred significantly higher level of protection than those delivered in conventional liposomes against hamster leptospirosis. Vaccine 2009 Nov 5; 27(47): 6537-45.

  • Syed M. Faisal, WeiWei Yan, Sean P. McDonough, and Yung-Fu Chang. Immune response and prophylactic efficacy of smegmosomes in hamster model of leptospirosis. Vaccine 2009 Oct 19; 27(44): 6129-36.

  • Syed M. Faisal, WeiWei Yan, Sean P. McDonough, and Yung-Fu Chang. Leptospira immunoglobulin-like protein A variable region (LigAvar) incorporated in Liposomes and PLGA-Microspheres produces a robust immune response correlating to protective immunity. Vaccine 2009, Jan 14;27(3):378-87.

  • Syed M. Faisal, WeiWei Yan, Chia-Sui Chen, Raghavan UM Palaniappan, Sean P. McDonough, and Yung-Fu Chang. Evaluation of protective immunity of Leptospira immunoglobulin like protein A (LigA) DNA vaccine against challenge in hamsters. Vaccine 2008 Jan 10; 26(2): 277-87.

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Mission: Development of sustainable and  globally competitive livestock industry through innovative technology.

Vision: To demonstrate excellence in promoting and commercializing leads in biotechnology and to produce globally competitive livestock products, pharmaceuticals and biologicals for animal health care.

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