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Name:
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Anand Srivastava
Scientist-D
Molecular Parasitology, Entomology, Host-pathogen interaction(s), Molecular interactions
anand[at]niab[dot]org[dot]in |
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Laboratory of Molecular Interactions
Education and training:
Dr. Anand Srivastava completed B.Sc. (1999) from University of Delhi, Delhi, and M.Sc. (2001; Biotechnology) from the Allahabad University, Allahabad, India. He did Ph.D. (2008) from Jawaharlal University (JNU) working at International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India. He then worked at Institut Pasteur, Paris (2008-2011) and Institut National de Transfusion Sanguine, Paris (2011-2012) as a Post-doctoral Fellow. He joined National Institute of Animal Biotechnology (NIAB) in 2013.
Research experience and interests:
Dr. Srivastava has vast experience in parasite biology. He has worked intensively on malaria parasite where his research focus was understanding molecular host-parasite interaction(s). Presently he is working on a veterinary important parasite Theileria. His research interests are to understand the molecular basis of the disease Theileriosis. He is also interested in understanding the biology of the vector (tick) which transmits the Theileria parasite.
Selected awards, honours and fellowships:
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Best Oral presentation award, 13th Conference on Vectors and Vector Borne Diseases, Chennai, 2017.
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Postdoctoral Fellowship, Fondation pour la Recherche Médicale (FRM), France (2011-2012).
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Keystone Symposia Scholarship, 2010.
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Fellowship to attend PHARE workshop, Martina Franca, Italy, 2009.
Selected publications:
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Prasanna Babu Araveti and Anand Srivastava. Curcumin induced oxidative stress causes autophagy and apoptosis in bovine leucocytes transformed by Theileria annulata. Cell Death Discovery Volume 5, Article number: 100 (2019)
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Prajna Parimita Kar and Anand Srivastava. Immuno-informatics Analysis to Identify Novel Vaccine Candidates and Design of a Multi-Epitope Based Vaccine Candidate Against Theileria parasites. Frontiers in Immunology 2018; 9: 2213.
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Anilkumar K, Reddy GV, Azad R, Yarla NS, Dharmapuri G, Srivastava A, Kamal MA, and Reddanna Pallu. Evaluation of Anti-Inflammatory Properties of Isoorientin Isolated from Tubers of Pueraria tuberosa. Oxidative Medicine and Cellular Longevity Volume 2017: 2017:5498054
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de Moraes LV, Dechavanne S, Sousa PM, Barateiro A, Cunha SF, Nunes-Silva S, Lima FA, Murillo O, Marinho CR, Gangnard S, Srivastava A, Braks JA, Janse CJ, Gamain B, Franke-Fayard B, Penha-Gonçalves C. 2016. A murine model for pre-clinical studies on Var2CSA-mediated pathology associated to malaria in pregnancy. Infection and Immunity 84(6):1761-4.
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Gangnard S, Lewit-Bentley A, Dechavanne S, Srivastava A, Amirat F, Bentley GA, Gamain B. 2015. Structure of the DBL3X-DBL4ε region of the VAR2CSA placental malaria vaccine candidate: insight into DBL domain interactions. Scientific Reports 5:14868.
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Dechavanne S, Srivastava A, Gangnard S, Nunes-silva S, Dechavanne C, Fievet N, Deloron P, Chêne A, Gamain B. 2015. The parity-dependent recognition of the DBL1X-3X suggests an important role of the VAR2CSA high affinity CSA-binding region in the development of the humoral response against placental malaria. Infection and Immunity 83(6):2466-74.
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Gullingsrud J, Milman N, Saveria T,
Chesnokov O, Williamson K, Srivastava A, Gamain B, Duffy PE, Oleinikov AV. 2015. High-throughput screening platform identifies small molecules that prevent sequestration of Plasmodium falciparum-infected erythrocytes. Journal of Infectious Diseases 211(7):1134-43.
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Srivastava A, Gangnard S, Dechavanne S, Amirat F, BentleyGA, Bentley GA and Gamain B. 2011. Var2CSA minimal CSA binding region is located within the N-terminal region. PLoS ONE 6(5):e20270.
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Rathore S, Jain S, Sinha D, Gupta M, Asad M, Srivastava A, Narayanan MS, Ramasamy G, Chauhan VS, Gupta D, and Mohmmed A. 2011. Disruption of a mitochondrial protease machinery in Plasmodium falciparum is an intrinsic signal for parasite cell death. Cell Death and Disease 2:e231.
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Avril M, Hathaway MJ, Srivastava A, Dechavanne S, Hommel M, Beeson JG, Smith JD, Gamain B. 2011. Antibodies to a full-length VAR2CSA immunogen are broadly strain-transcendent but do not cross-inhibit different placental-type parasite isolates. PLoS ONE
6(2):e16622.
Detailed profile
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